Current evidence and clinical experience suggest that CBD influences the body’s endocannabinoid system, which plays a role in pain modulation, inflammation, stress response, and sleep-wake regulation. Because PICO IV is delivered intravenously, patients often experience faster onset of effects compared with oral CBD.
Supporting Chronic Pain and Inflammation
CBD may modulate inflammatory signaling and pain perception pathways. For high-performers managing the physical toll of training, travel, or chronic conditions, this can mean measurable relief without the cognitive impairment of traditional pain management.
Promoting Nervous System Calm and Stress Resilience
Chronic stress dysregulates your nervous system. CBD may help address anxiety-like symptoms, fight-or-flight overload, and emotional overwhelm. This isn’t about feeling sedated. It’s about recalibrating so you can lead with clarity instead of operating from a place of constant activation.
Enhancing Sleep Quality
By addressing underlying contributors like pain, stress, and nervous system hyperactivity, CBD may improve sleep architecture. Better sleep means better recovery, sharper cognition, and sustained performance.
Supporting Cognitive Clarity and Focus
When chronic stress or discomfort disrupts your mental bandwidth, CBD may help restore the focus and processing speed your work demands
Important Note
Results vary significantly from person to person. PICO IV CBD therapy is not a cure or guaranteed outcome for any condition. Treatment decisions at Awaken IV are grounded in realistic expectations, careful screening, and a clear understanding of both potential benefits and limitations.
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Schedule A Consultation
PICO IV CBD therapy is not appropriate for everyone, and it is not intended to replace primary medical care or prescribed medications.
You may be considered for this therapy if you:
You may be considered for this therapy if you:Experience ongoing stress, nervous system dysregulation, or anxiety-like symptoms You’ve already addressed sleep hygiene, nutrition, and lifestyle foundations, but you’re still operating in a state of constant activation. You need a clinical tool that goes deeper.
Experience ongoing stress, nervous system dysregulation, or anxiety-like symptomsLive with chronic pain, inflammatory conditions, or autoimmune flare patterns You’re seeking additional supportive options in coordination with your medical team. You understand this is part of a broader strategy, not a standalone fix.
Live with chronic pain, inflammatory conditions, or autoimmune flare patternsHave tried oral CBD products and found them insufficient or inconsistent You’re interested in a more controlled, higher-bioavailability option delivered in a medical setting with precise dosing and monitoring.
Have tried oral CBD products and found them insufficient or inconsistentValue a cautious, medically supervised, data-driven approach You’re not interested in self-experimenting with unregulated products. You want expert guidance, sterile protocols, and measurable outcomes.
Value a cautious, medically supervised, data-driven approachYou may not be a candidate if you:
You may not be a candidate if you:A detailed health history, medication review, and sometimes coordination with your prescribing providers are mandatory before moving forward.
You need to understand the regulatory context before proceeding.
You need to understand the regulatory context before proceeding.CBD in injectable form is under active review by federal regulators. The U.S. Food and Drug Administration (FDA) has issued a warning letter to Pico IV Inc. related to how its intravenous CBD product has been marketed under federal law. The agency emphasized that injectable products are especially concerning because anything delivered directly into the bloodstream bypasses many of the body’s natural defenses and can pose risks of serious or life-threatening harm if contaminated, improperly formulated, or misused.
The FDA has also stated that, outside of one prescription CBD product approved for specific seizure disorders, it has not approved CBD products for the diagnosis, treatment, cure, or prevention of disease. Marketing CBD products (especially injectable forms) with disease claims is a focus of ongoing enforcement.
Awaken IV’s approach is built around:
Awaken IV’s approach is built around:PICO IV CBD therapy is not intended to diagnose, treat, cure, or prevent any disease and should not be considered a substitute for the care of your primary physician or specialist.
We don’t hide from these facts. We lead with them. Because high-performers deserve complete transparency, not marketing spin.
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Schedule A Consultation
At Awaken IV, we follow a careful, medically guided evaluation process to ensure every treatment is safe, effective, and customized to your goals.
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Schedule A ConsultationYour provider will help you decide whether CBD IV therapy, another IV option, or a non-IV approach is most appropriate for your goals and medical context.
Schedule A Consultation
Schedule A Consultation
Will PICO IV CBD make me feel “high”?
Will PICO IV CBD make me feel “high”?CBD is non-intoxicating and does not produce the classic “high” associated with THC. Many patients report feeling more relaxed, grounded, or occasionally drowsy after an infusion. Individual responses vary, and your dose and infusion rate are tailored to safety and comfort
Is this treatment FDA-approved?
Is this treatment FDA-approved?The only FDA-approved CBD medication is a prescription oral product for specific seizure disorders, not for IV use. PICO IV CBD therapy is not FDA-approved for any indication and should be considered an off-label, experimental wellness-oriented use provided in a medical setting with full informed consent.
Is PICO IV CBD therapy legal?
Is PICO IV CBD therapy legal?PICO IV is produced from federally legal hemp-derived CBD and is sold only to licensed medical practices and IV clinics. However, the FDA has raised concerns about how injectable CBD products are marketed and about unapproved therapeutic claims, so the regulatory landscape is evolving and must be navigated carefully by clinics.
What are the possible side effects?
What are the possible side effects?Reported side effects of CBD, especially at higher doses, can include drowsiness, fatigue, dry mouth, lightheadedness, changes in appetite, or mild digestive upset. IV administration can also very rarely trigger infusion-related reactions or changes in blood pressure or heart rate. The risk of serious complications is minimized through sterile technique, screening, monitoring, and immediate access to medical staff, but no IV therapy is risk-free.
Can PICO IV CBD interact with my medications?
Can PICO IV CBD interact with my medications?Yes. CBD is known to interact with certain medications, especially those processed by liver enzymes such as the cytochrome P450 system, including some blood thinners, anti-seizure medications, and psychiatric drugs. A thorough medication review and, when needed, communication with your prescribing providers are required befo
How many treatments will I need and how often?
How many treatments will I need and how often?Frequency is highly individualized and depends on your goals, underlying conditions, and how you respond to initial infusions. Some patients explore a short series of closely spaced sessions. Others use CBD IV therapy sparingly for specific flare-ups or high-stress periods, always under guidance.
How many treatments will I need and how often?
How many treatments will I need and how often?Frequency is highly individualized and depends on your goals, underlying conditions, and how you respond to initial infusions. Some patients explore a short series of closely spaced sessions. Others use CBD IV therapy sparingly for specific flare-ups or high-stress periods, always under guidance.
Can I combine PICO IV CBD with other IV drips?
Can I combine PICO IV CBD with other IV drips?In some cases, CBD infusions can be sequenced with or added to other IV therapies, but decisions about combinations, timing, and dosing are made on a case-by-case basis to protect safety and avoid over-treating. Your provider will design a plan that reflects your lab data, symptoms, and overall protocol rather than stacking multiple advanced infusions without a clear rationale.
Can PICO IV CBD replace my existing medications or mental health care?
Can PICO IV CBD replace my existing medications or mental health care?No. CBD IV therapy is not a substitute for prescribed medications, psychotherapy, or specialist care. You should never stop or change medications without working directly with your prescribing clinician. Awaken IV’s team is happy to coordinate with your existing providers to ensure that any IV therapy supports, rather than disrupts, your overall treatment plan.
How do I find out if I am a good fit?
How do I find out if I am a good fit?The first step is to schedule a consultation, during which your provider will review your history, medications, goals, and risk factors and then recommend either PICO IV CBD, an alternative therapy, or no IV treatment at all.