Platelet-rich plasma (PRP) therapy is one of the most talked-about regenerative treatments today, from restoring thinning hair to easing joint pain and refreshing skin.
But if you’re considering it, you probably have the same question many patients ask: is PRP treatment permanent?
The short answer: No, PRP is not permanent.
Results can last a year or longer, but most people need follow-up sessions to maintain the benefits.
How long it lasts depends on your health, the condition being treated, and your treatment plan.
What Does “Permanent” Really Mean With PRP?
When people ask if PRP is permanent, they usually want to know if one round of treatments will last forever.
PRP works by using your own platelets to release growth factors, repair tissues, and stimulate new cell activity.
Because your body continues to age and regenerate at its own pace, those changes don’t “freeze in time.”
PRP can restart or boost healing, but it doesn’t completely stop the natural progression of aging or conditions like hair loss.
Does PRP Regrow Hair Permanently?
For hair restoration, PRP is one of the safest and most natural options.
But does PRP regrow hair permanently?
The answer is no.
Here’s what research and real-world results show:
- A 2022 clinical review found that PRP significantly improved hair density and thickness, but results typically lasted 12–18 months without maintenance.
- Most patients see visible improvements within 3–6 months of starting treatment.
- To keep results, many providers recommend booster sessions every 6–12 months.
PRP slows down shedding and strengthens follicles, but it doesn’t cure the genetic or hormonal causes of hair loss.
Without ongoing care, thinning usually resumes.
How Long Does PRP Last for Other Conditions?
PRP is widely used beyond hair, in sports medicine, orthopedics, and aesthetics.
Longevity varies by condition:
- Joint injections for pain and injuries: Studies show relief lasting 6 months to 2 years, depending on severity and lifestyle. Some patients schedule yearly boosters.
- Skin rejuvenation: Smoother texture and reduced fine lines may last around 12 months before touch-ups are helpful.
- Hair restoration: As noted, results last about a year on average before a maintenance plan is needed.
In short, PRP results are long-lasting, not permanent.
Factors That Affect PRP Longevity
Why do some people see results that last longer than others?
A few key factors make the difference:
- Condition stage: Early hair loss or mild joint issues respond best.
- Age and overall health: Younger, healthier patients often get longer-lasting results.
- Treatment plan: Completing the recommended series (often 3–4 sessions) and sticking to maintenance visits is critical.
- Lifestyle habits: Nutrition, sleep, stress, and smoking all impact how well your body responds.
Is PRP Permanent Compared to Other Options?
It helps to see PRP in context with other treatments:
| Treatment | Permanent? | Pros | Cons |
| PRP therapy | No, but long-lasting with maintenance | Natural, non-surgical, uses your own blood | Requires ongoing boosters |
| Hair transplant | Yes, transplanted follicles are permanent | One-time, lasting results | Surgical, higher cost, recovery time |
| Medications (minoxidil, finasteride) | Not permanent | Easy to use, widely available | Results fade if stopped, possible side effects |
So, is PRP permanent?
No, but it offers a middle ground: safer and less invasive than surgery, with longer-lasting effects than many medications.
How to Make PRP Results Last Longer
If you’re considering PRP, there are ways to extend the results:
- Commit to the full initial series, usually 3–4 sessions a few weeks apart.
- Book regular maintenance sessions every 6–12 months.
- Support your body’s healing with good nutrition, exercise, and quality sleep.
- Combine treatments if recommended, for example, PRP plus low-level laser therapy for hair, or PRP plus physical therapy for joint recovery.
GET THE MOST OUT OF YOUR TREATMENT
Bottom Line: Is PRP Treatment Permanent
PRP treatment isn’t permanent, but it can deliver results that last a year or more with proper maintenance.
For many people, it’s a natural and effective way to restore hair, relieve pain, or refresh skin without surgery or harsh medications.
At Awaken IV we specialize in creating personalized PRP treatment plans designed to maximize your results and keep them lasting as long as possible.
If you’re ready to see what PRP can do for you, contact our team today to get started.
FAQs: Is PRP Treatment Permanent
How long do PRP results last?
PRP results usually last 12 to 18 months, though some people see benefits for up to two years with maintenance sessions.
Do I need to do PRP forever?
No, but most people need ongoing treatments every 6 to 12 months to maintain results. Without boosters, the effects fade over time.
What happens after you stop PRP?
If you stop PRP, your body gradually returns to its natural state. For hair, shedding may restart, and for joints, pain or stiffness may come back.
Is 2 PRP sessions enough?
Two sessions may help some people, but most providers recommend at least three to four sessions to build strong, lasting results.
What is the downside of PRP?
The downsides are that it isn’t permanent, can be costly over time, and may cause mild soreness or swelling after injections. Serious side effects are rare.
What are the signs that PRP is working?
For hair, you’ll notice less shedding and thicker strands. For joints, pain decreases and mobility improves. For skin, texture and tone look healthier.
Does PRP work for hair?
Yes, PRP can regrow hair, increase thickness, and slow down shedding, especially in people with early-stage hair loss.
Does PRP help knee pain?
Yes, many patients report reduced knee pain and improved function after PRP, with relief lasting six months to two years depending on severity.
Does PRP help with herniated discs?
PRP may help with herniated discs by reducing inflammation and pain, but results vary. It’s best used as part of a broader treatment plan.





